DEVICES AND METHODS FOR TISSUE ENGINEERING

摘要

A bioactive tissue scaffold is fabricated from glass fiber that forms a rigid three-dimensional porous matrix having a bioactive composition. Porosity in the form of interconnected pore space is provided by the pore space between the glass fiber in the porous matrix. Mechanical properties such as strength, elastic modulus, and pore size distribution is provided by the three-dimensional matrix that is formed by bonded overlapping and intertangled fibers. The bioactive tissue scaffold can be formed from raw materials that are not bioactive, but rather precursors to bioactive materials. The bioactive tissue scaffold supports tissue in-growth to provide osteoconductivity as a resorbable tissue scaffold, used for the repair of damaged and/or diseased bone tissue.