发明名称 |
Products for altering IL-33 activity and methods thereof |
摘要 |
Products for altering IL-33 activity including antibodies that specifically bind to an epitope with the polypeptide sequence of IL-33 such as antibodies that specifically bind to a protease cleavage region of IL-33 comprising the amino acid sequence of SEQ ID No. 17, or SEQ ID NO. 16, or SEQ ID NO. 10; isolated IL-33 polypeptide(s); and compositions comprising a soluble IL-33 receptor linked to an enzyme capable of cleaving IL-33 or an antibody that binds to IL-33 linked to an enzyme capable of cleaving IL-33. The invention also relates to methods of altering IL-33 activity using the products described herein.
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申请公布号 |
US8119771(B2) |
申请公布日期 |
2012.02.21 |
申请号 |
US20080451053 |
申请日期 |
2008.04.28 |
申请人 |
MARTIN SEAMUS J.;THE PROVOST, FELLOW AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN |
发明人 |
MARTIN SEAMUS J. |
分类号 |
C07K14/54 |
主分类号 |
C07K14/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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