PROCESS FOR PRODUCTION OF PURIFIED CHLOROGENIC ACID-CONTAINING PHARMACEUTICAL PREPARATION

摘要

PROBLEM TO BE SOLVED: To provide a process for the production of a purified chlorogenic acid-containing pharmaceutical preparation useful in the production of chlorogenic acid-containing beverages which rarely become cloudy even in an acid region.

SOLUTION: The process for the production of a purified chlorogenic acid-containing pharmaceutical preparation includes: the first step of dispersing or dissolving a starting chlorogenic acid-containing composition in a mixed solvent consisting of an organic solvent and water in the presence of acid clay or activated clay; the second step of removing a precipitate formed in the dispersion or solution obtained in the first step; the third step of adjusting the solution obtained in the second step to a chlorogenic acid concentration of 1.5 to 10 mass% and a pH of 2 to 4; and the fourth step of removing a precipitate formed in the adjusted solution obtained in the third step.

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