发明名称 METHOD OF PHOTODYNAMIC THERAPY OF SUBJECTS WITH MALIGNANT TUMOURS
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to medicine, photodynamic therapy of tumours. Photosensitiser (PS), in particular radachlorine is added to nanoparticles of emulsion of perfluorocarbons (PFC), consisting of perfluorodecalin and perfluoromethylcyclohexylpiperidine, stabilised with proxanol 268 solution. Emulsion of PFC with PS is added to stem cells of bone marrow (SCBM), in particular, autologic. Their joined cultivation is carried out, after which SCBM is introduced to subject with malignant tumour, in particular breast tumour. Zone of tumour growth is subjected to impact by light irradiation in dose sufficient for complete or partial tumour destruction. Subject can be represented by a mammal, in particular, human being. ^ EFFECT: method ensures targeted impact, complete or partial tumour regress, excludes systemic phototoxic injuries. ^ 6 cl, 3 ex, 3 dwg
申请公布号 RU2440158(C2) 申请公布日期 2012.01.20
申请号 RU20100106294 申请日期 2010.02.25
申请人 BELYJ JURIJ ALEKSANDROVICH;KUKUSHKIN NIKOLAJ IL'ICH;SKLIFAS ALLA NIKOLAEVNA;TEMNOV ANDREJ ALEKSANDROVICH;TERESHCHENKO ALEKSANDR VLADIMIROVICH 发明人 BELYJ JURIJ ALEKSANDROVICH;KUKUSHKIN NIKOLAJ IL'ICH;SKLIFAS ALLA NIKOLAEVNA;TEMNOV ANDREJ ALEKSANDROVICH;TERESHCHENKO ALEKSANDR VLADIMIROVICH
分类号 A61K31/02;A61K31/28;A61N5/067;A61P35/00 主分类号 A61K31/02
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