摘要 |
<P>PROBLEM TO BE SOLVED: To provide a prophylactic or therapeutic agent of chorioretinal denaturation diseases without substantially accompanying neovascularization, e.g. atrophic age-related macular degeneration, retinitis pigmentosa, gyrate atrophy of the choroid and retina, and further chorioretinal disorders associated with the above diseases. <P>SOLUTION: This compound expressed by formula (1) or its pharmaceutically acceptable salt has an inhibitory effect toward photo receptor cell death in a mouse light disorder model. Therefore, it is useful as the prophylactic or therapeutic agent of chorioretinal denaturation diseases without substantially accompanying neovascularization, eg. atrophic age-related macular degeneration, retinitis pigmentosa, gyrate atrophy of the choroid and retina and further chorioretinal disorders associated with the diseases. <P>COPYRIGHT: (C)2012,JPO&INPIT |