NOVEL 5,7-DISUBSTITUTED [1,3]THIAZOLO[4,5-d]PYRIMIDINE-2-(3H)-AMINE DERIVATIVES AND USE THEREOF IN THERAPY

摘要

FIELD: chemistry. ^ SUBSTANCE: invention relates to compounds of general formula where R1 denotes CH3; R2 denotes halogen or CN; R3 denotes H or CH3; R4 denotes H or CH3; n equals 1; and pharmaceutically acceptable salts thereof. The invention also relates to a pharmaceutical composition and use of compounds of formula (I) in preparing a medicinal agent, having CX3CR1 receptor antagonist activity. ^ EFFECT: compounds can be used as CX3CR1 receptor antagonists. ^ 13 cl, 1 tbl, 10 ex