COATED TABLETS OF 6-(5-CHLORO-2-PYRIDYL) -5-[ (4-METHYL-1-PIPERAZINYL) CARBONYLOXY]-7-OXO-6, 7-DIHYDRO-5H-PYRROL O [3,4-B] PYRAZINE AND METHODS FOR MEASURING EFFECTIVENESS OF COATING

摘要

Coated tablets of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided. The tablets minimize the perceived bitterness of the medicament. A method for analyzing instantaneous dissolution of sub-microgram quantities of core material is also disclosed.