发明名称 |
METHODS FOR CHARACTERIZING AGONISTS AND PARTIAL AGONISTS OF TARGET MOLECULES |
摘要 |
In one aspect, the present invention provides methods of determining whether an agent is more like a partial agonist of a target molecule than a full agonist of the same target molecule. In another aspect, the present invention provides methods to select a candidate compound that may reduce blood plasma glucose concentration in a mammal. Populations of genes are provided that are useful in the practice of the present invention. |
申请公布号 |
US2011294696(A1) |
申请公布日期 |
2011.12.01 |
申请号 |
US201113209156 |
申请日期 |
2011.08.12 |
申请人 |
TAN YEJUN;DAI HONGYUE;LUM PEK YEE;THOMPSON JOHN RYAN;BERGER JOEL PETER;MUISE ERIC STANLEY;RAUBERTAS RICHARD F.;WONG KENNY KIN CHUNG;MERCK SHARP & DOHME CORP. |
发明人 |
TAN YEJUN;DAI HONGYUE;LUM PEK YEE;THOMPSON JOHN RYAN;BERGER JOEL PETER;MUISE ERIC STANLEY;RAUBERTAS RICHARD F.;WONG KENNY KIN CHUNG |
分类号 |
C40B30/04 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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