发明名称 SORBIC AND BENZOIC ACID AND DERIVATIVES THEREOF ENHANCE THE ACTIVITY OF A NEUROPHARMACEUTICAL
摘要 Methods and compositions are provided for treating neuropsychiatric disorders such as schizophrenia, depression, attention deficit disorder, mild cognitive impairment, dementia, and bipolar disorder. The methods entail administering to a patient diagnosed as having a neuropsychiatric disorder ( e . g ., schizophrenia, depression, attention deficit disorder, mild cognitive impairment, dementia bipolar disorder, etc .) or as at risk for a neuropsychiatric disorder a benzoic acid, benzoic acid salt, and/or benzoic acid derivative, and/or a sorbic acid, sorbic acid salt, and/or sorbic acid derivative, in combination with a neuropharmacological agent ( e . g ., an antipsychotic, an antidepressant, medications for attention deficit and hyperactivity disorder, cognitive impairment, or dementia, etc. ) where the benzoic acid, benzoic acid salt, or benzoic acid derivative, and/or a sorbic acid, sorbic acid salt, and/or sorbic acid derivative, is in an amount sufficient to increase the efficacy of the neuropharmacological agent.
申请公布号 EP2389187(A1) 申请公布日期 2011.11.30
申请号 EP20100733788 申请日期 2010.01.19
申请人 LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER 发明人 TSAI, GUOCHUAN, EMIL
分类号 A61K31/192;A61K31/19;A61K31/196;A61K31/22;A61K31/235;A61K31/245;A61K45/06;A61P25/00;A61P25/18;A61P25/22;A61P25/24;A61P25/26;A61P25/28 主分类号 A61K31/192
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