发明名称 |
Humanized anti-CD70 binding agents and uses thereof |
摘要 |
Disclosed are CD70 binding agents, such as humanized anti-CD70 antibodies and fragments and derivatives, that exert a cytotoxic, cytostatic or immunomodulatory on CD70 expressing cells, as well as pharmaceutical compositions and kits comprising the antibody, fragment or derivative. Also disclosed are methods for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the CD70 binding agents or pharmaceutical compositions. |
申请公布号 |
US8067546(B2) |
申请公布日期 |
2011.11.29 |
申请号 |
US20060912096 |
申请日期 |
2006.04.19 |
申请人 |
MCDONAGH CHARLOTTE;CARTER PAUL;MCEARCHERN JULIE;LAW CHE-LEUNG;SEATTLE GENETICS, INC. |
发明人 |
MCDONAGH CHARLOTTE;CARTER PAUL;MCEARCHERN JULIE;LAW CHE-LEUNG |
分类号 |
C12P21/08;A61K39/00;A61K39/395;C07K16/00;C07K17/00;C07K17/14 |
主分类号 |
C12P21/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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