发明名称 |
Gyrase inhibitors and uses thereof |
摘要 |
The present invention relates to methods of treating, preventing, or lessening the severity of resistant bacterial infections in mammals, utilizing compounds of formula I or formula VII or pharmaceutically salts thereof. The present invention also relates to methods of using compounds of formula I or formula VII in combination with one or more additional antibacterial agents and/or one or more additional therapeutic agents that increase the susceptibility of bacterial organisms to antibiotics. |
申请公布号 |
US8067606(B2) |
申请公布日期 |
2011.11.29 |
申请号 |
US20090483312 |
申请日期 |
2009.06.12 |
申请人 |
CHARIFSON PAUL;DEININGER DAVID;GRILLOT ANNE-LAURE;LIAO YUSHENG;RONKIN STEVEN;STAMOS DEAN;PEROLA EMANUELE;WANG TIANSHENG;LETIRAN ARNAUD;DRUMM JOSEPH;VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
CHARIFSON PAUL;DEININGER DAVID;GRILLOT ANNE-LAURE;LIAO YUSHENG;RONKIN STEVEN;STAMOS DEAN;PEROLA EMANUELE;WANG TIANSHENG;LETIRAN ARNAUD;DRUMM JOSEPH |
分类号 |
C07D401/14;A61K31/4439;A61K31/444;A61K31/506;A61P31/04;C07D403/04;C07D403/14;C07D405/04;C07D405/14;C07D413/14;C07D417/14;C07D471/04;C07D487/04;C07D491/04 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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