摘要 |
The invention is directed to an apparatus and method for purifying a protein. The apparatus involves the use of a capture chromatography resin, a depth filter arranged after the capture chromatography resin, and a mixed-mode chromatography resin arranged after the depth filter. The method involves providing a sample containing the protein, processing the sample through a capture chromatography resin, a depth filter, and a mixed-mode chromatography resin. A membrane adsorber or monolith may be substituted for the mixed-mode chromatography column. |
申请人 |
ABBOTT LABORATORIES;WANG, CHEN;HICKMAN, ROBERT, K.;LUNDELL, EDWIN, O.;HEGEDUS, ROY, D. |
发明人 |
WANG, CHEN;HICKMAN, ROBERT, K.;LUNDELL, EDWIN, O.;HEGEDUS, ROY, D. |