发明名称 |
METHODS OF TREATING COGNITIVE DISORDERS BY INHIBITION OF GPR12 |
摘要 |
The present invention provides methods for screening a pharmaceutical agent for its ability to modulate long term memory formation, performance of a hippocampal-dependent cognitive task or Gpr12 function. The present invention also provides methods for modulating long term memory formation or performance of a hippocampal-dependent cognitive task by modulating Gpr12-dependent protein expression. The present invention further provides methods for treating a defect in long term memory formation by inhibiting Gpr12 function and methods for treating a defect in performance of a hippocampal-dependent cognitive task by inhibiting Gpr12 function. |
申请公布号 |
US2011281936(A1) |
申请公布日期 |
2011.11.17 |
申请号 |
US201113169739 |
申请日期 |
2011.06.27 |
申请人 |
PETERS MARCO;SCOTT RODERICK EUAN MILNE;TULLY TIMOTHY P. |
发明人 |
PETERS MARCO;SCOTT RODERICK EUAN MILNE;TULLY TIMOTHY P. |
分类号 |
A61K31/713;A61P25/00;C12Q1/68 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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