发明名称 |
IMPROVED CELL CULTURE MEDIUM |
摘要 |
<p>A cell culture medium with high content of choline chloride is provided. The cell culture media further comprise only moderate amounts of amino acids, in particular the amount of glutamine in the cell culture media is limited. The cell culture media can be used for large scale production of polypeptides using cell cultures. The cell culture media with high content of choline chloride are particularly suitable for fed-batch cell culture whereby cell viabilities stay at a higher level for a longer time and high polypeptide titers although limited amounts of amino acids are used.</p> |
申请公布号 |
CA2797140(A1) |
申请公布日期 |
2011.11.03 |
申请号 |
CA20112797140 |
申请日期 |
2011.04.25 |
申请人 |
NOVARTIS AG |
发明人 |
BUDACH, WOLFGANG ERNST GUSTAV;CHASSIN, HELENE C.;DORSCH, KERSTIN |
分类号 |
C12N5/00 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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