| 发明名称 |
9-substituted minocycline compounds |
| 摘要 |
The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
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| 申请公布号 |
US8048867(B2) |
申请公布日期 |
2011.11.01 |
| 申请号 |
US20040839023 |
申请日期 |
2004.05.04 |
| 申请人 |
TRUSTEES OF TUFTS COLLEGE;PARATEK PHARMACEUTICALS, INC. |
发明人 |
NELSON MARK L.;FRECHETTE ROGER;VISKI PETER;ISMAIL MOHAMED Y.;BOWSER TODD;DUMORNAY JIMMY;RENNIE GLEN;LIU GUI;KOZA DARRELL J.;SHEAHAN PAUL;STAPLETON KAREN;HAWKINS PAUL;BHATIA BEENA;VERMA ATUL K.;MCINTYRE LAURA;WARCHOL TADEUSZ;MESSERSMITH DAVID |
| 分类号 |
A61K31/59;C07D317/58;A61K31/65;A61P31/04;C07C237/00;C07C237/26;C07C255/59;C07C271/22;C07C271/28;C07C271/30;C07C271/58;C07C275/30;C07C275/34;C07C275/38;C07C275/40;C07C275/42;C07C275/50;C07C275/54;C07C279/18;C07C311/06;C07C311/13;C07C311/21;C07C331/24;C07C333/08;C07C335/22;C07C381/10;C07C401/00;C07D295/155;C07D317/62;C07F9/40 |
主分类号 |
A61K31/59 |
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