发明名称 |
METHOD OF SYNTHESIZING A 5-OXO-CONJUGATED FATTY ACID |
摘要 |
<p>There is provided a novel chemical synthetic method for the preparation of a 5-oxo-ETE and related compounds. The method is based on a short and efficient synthesis of 5-oxo-ETE from commercially available Arachidonic acid. The method is based on the surprising discovery that a 5-oxo-conjugated fatty acid may be efficiently converted into the corresponding 5-oxo-conjugated fatty acid by reaction with the Dess-Martin reagent (1,1,1-triacetoxy-1,1-dihydro-1,2-benziodoxol-3(1H)-one)in the presence of pyridine or a substituted pyridine.</p> |
申请公布号 |
WO2011131619(A1) |
申请公布日期 |
2011.10.27 |
申请号 |
WO2011EP56128 |
申请日期 |
2011.04.18 |
申请人 |
SYDDANSK UNIVERSITET;ULVEN, TROND;TYAGI, RAHUL |
发明人 |
ULVEN, TROND;TYAGI, RAHUL |
分类号 |
C07C17/02;C07C51/373 |
主分类号 |
C07C17/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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