发明名称 |
METHOD FOR TREATING SOLID TUMORS |
摘要 |
Provided herein are methods for treating a solid tumor in a subject in need thereof by activating an immune response against a tumor antigen. Also provided are methods for treating a solid tumor in a subject in need thereof by activating antigen-presenting cells and eliciting an immune response against a tumor antigen. Also provided herein are optimized therapeutic treatments of solid tumors, which comprise determining the presence, absence or amount of a biomarker after the therapy has been administered, and determining whether a subsequent dose of the therapy should be maintained, increased, or decreased based on the biomarker assessment. |
申请公布号 |
WO2011130566(A2) |
申请公布日期 |
2011.10.20 |
申请号 |
WO2011US32572 |
申请日期 |
2011.04.14 |
申请人 |
BELLICUM PHARMACEUTICALS, INC.;SLAWIN, KEVIN;SPENCER, DAVID;LAPTEVA, NATALIA |
发明人 |
SLAWIN, KEVIN;SPENCER, DAVID;LAPTEVA, NATALIA |
分类号 |
A61K39/00;A61K31/711;A61P35/00;A61P35/04 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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