发明名称 |
Flux Enhancement in Continuous Glucose Monitoring |
摘要 |
One aspect of the invention is a method of in vivo monitoring of an individual's interstitial fluid glucose concentration comprising inserting a plurality of tissue piercing elements through a stratum corneum layer of an area of the individual's skin. The tissue piercing elements each comprise a distal end in fluid communication with interstitial fluid of the individual, and a proximal end in fluid communication with a sensing zone located outside of the patient's body. An interior space extends between the distal and proximal ends of the tissue piercing elements. A sensing fluid fills substantially the entire interior space and the sensing fluid concentration comprises a concentration of citrate in a buffer solution. The concentration of citrate may range from 100 mM to 200 mM, preferably 135-165 mM.
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申请公布号 |
US2011257497(A1) |
申请公布日期 |
2011.10.20 |
申请号 |
US20110985229 |
申请日期 |
2011.01.05 |
申请人 |
TAMADA JANET;JINA ARVIND N;LEE JONATHAN |
发明人 |
TAMADA JANET;JINA ARVIND N.;LEE JONATHAN |
分类号 |
A61B5/145 |
主分类号 |
A61B5/145 |
代理机构 |
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地址 |
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