发明名称 Guanidine-containing compounds useful as muscarinic receptor antagonists
摘要 The invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein R1-3, R5-7, a, X, Y, Y′, Y″, and Z are as defined in the specification. These compounds are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes for preparing such compounds and methods of using such compounds to, for example, treat pulmonary disorders such as chronic obstructive pulmonary disease and asthma.
申请公布号 US8039489(B2) 申请公布日期 2011.10.18
申请号 US201113096651 申请日期 2011.04.28
申请人 THERAVANCE, INC. 发明人 JI YUHUA;HUSFELD CRAIG;MU YONGQI;LEE RICK;LI LI
分类号 A61K31/4439;A61K31/40;A61K31/4025;C07D207/12;C07D401/12;C07D405/12;C07D409/12 主分类号 A61K31/4439
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