发明名称 PEPTIDE VACCINE USING MIMIC MOLECULE OF AMYLOID BETA-PEPTIDE
摘要 <p>This invention is intended to discover a peptide that induces production of an antibody specific for an abnormal amyloid ² peptide from mimic peptides of the amyloid ² peptide and to utilize the same as a vaccine or immunogen. This invention relates to a pharmaceutical composition containing a peptide consisting of 8 to 30 amino acid residues, wherein the peptide comprises at least one of an amino acid sequence represented by formula (I): Tyr-Gly-Thr-Lys-Pro-Trp-Met (I), and an amino acid sequence represented by formula (II): Leu-Asp-Ile-Phe-Ala-Pro-Ile (II); or a conjugate of such peptide and a carrier.</p>
申请公布号 EP2226081(A4) 申请公布日期 2011.10.12
申请号 EP20080841003 申请日期 2008.10.22
申请人 KAGOSHIMA UNIVERSITY 发明人 SUGIMURA, KAZUHISA
分类号 A61K39/00;A61P25/28;A61P43/00;C07K14/47 主分类号 A61K39/00
代理机构 代理人
主权项
地址