发明名称 |
Herpes Simplex Virus Complex |
摘要 |
There is provided an HSV complex which comprises an avirulent HSV and a targeting agent which allows the HSV particle to infect and lyse a specific targeted cell. The inventors have found a way in which avirulent HSV can be targeted to disease cells, e.g. cancer cells, by incorporating an antibody binding domain into one or more viral glycoproteins. |
申请公布号 |
US2011244576(A1) |
申请公布日期 |
2011.10.06 |
申请号 |
US201113086215 |
申请日期 |
2011.04.13 |
申请人 |
CRUSADE LABORATORIES LIMITED |
发明人 |
BROWN SUSANNE MOIRA;CONNER JOE |
分类号 |
C12N15/09;C12N15/64;A61K35/76;A61K47/48;A61K48/00;A61P35/00;C07K14/005;C07K14/82;C07K16/00;C07K19/00;C12N7/00;C12N15/86 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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