发明名称 |
Polymorphisms in ABCB1 associated with a lack of clinical response to medicaments |
摘要 |
The present invention relates to methods, compositions and kits for determining the prognosis of a clinical response in a human patient to a medicament which acts in the central nervous system and which is a substrate of the ABCB1 protein. Further, the invention relates to a combination of medicaments for the treatment of human patients having specific polymorphisms in the ABCB1 gene. |
申请公布号 |
US8030033(B2) |
申请公布日期 |
2011.10.04 |
申请号 |
US20050596177 |
申请日期 |
2005.05.12 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSHAFTEN E.V. |
发明人 |
UHR MANFRED;HOLSBOER FLORIAN;BINDER ELISABETH;MUELLER-MYHSOK BERTRAM |
分类号 |
C12P19/34;C12Q1/68 |
主分类号 |
C12P19/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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