| 发明名称 |
USE OF COMPOUNDS WITH A 2-CYCLOPENTENONE STRUCTURE FOR THE INHIBITION OF ENZYMES OF THE FAMILY OF ALDO-KETO REDUCTASES |
| 摘要 |
<p>The invention relates to the use of a series of compounds having a 2-cyclopentenone nucleus substituted by alkyl and alkenyl chains that are proven inhibitors of aldo-keto reductase (AKR) enzymes, specifically AKR1 B1 and AKR1 B10. Consequently, the compounds of the invention can be used for the treatment of pathological conditions or diseases involving said enzymes.</p> |
| 申请公布号 |
WO2011117453(A1) |
申请公布日期 |
2011.09.29 |
| 申请号 |
WO2011ES70201 |
申请日期 |
2011.03.25 |
| 申请人 |
DIEZ DACAL, BEATRIZ;CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC);PEREZ-SALA GOZALO, MARIA DOLORES |
发明人 |
PEREZ-SALA GOZALO, MARIA DOLORES;DIEZ DACAL, BEATRIZ |
| 分类号 |
A61K31/5575 |
主分类号 |
A61K31/5575 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
