| 摘要 |
Disclosed is a pharmaceutical composition for controlled release, comprising a core material containing methylphenidate, and a plurality of particles for controlled release, containing a polymer coating layer for controlled release, formed on the core material. The plurality of particles for controlled release is divided into two or more groups based on the average thickness of the polymer coating layer for controlled release. The particle groups are identical in terms of the composition of the polymer in the polymer coating layer, but are different in terms of the average thickness of the coated layer. The pharmaceutical composition for controlled release according to the present invention may control the release pattern of methylphenidate contained in the core material as desired, and can be used as an oral formulation in a variety of forms such as quick dissolving tablets, etc. |
