发明名称 |
METHOD FOR OBTAINING BIOLOGICALLY ACTIVE RECOMBINANT HUMAN G-CSF |
摘要 |
Provided is a method of obtaining biologically active recombinant human G-CSF from inclusion bodies, wherein the solubilization and refolding process can be performed at ambient temperature and the purification step comprises reversed phase chromatography (RP), in particular RP-HPLC. The G-CSF preparation so obtained is characterized by high purity and homogeneity.
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申请公布号 |
CA2789615(A1) |
申请公布日期 |
2011.09.22 |
申请号 |
CA20112789615 |
申请日期 |
2011.03.17 |
申请人 |
BIOGENERIX GMBH |
发明人 |
HINDERER, WALTER;SCHECKERMANN, CHRISTIAN |
分类号 |
C07K14/535 |
主分类号 |
C07K14/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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