发明名称 |
HEPARAN SULFATE REPLACEMENT THERAPY |
摘要 |
The present invention relates to a method for inhibiting oxidative damage of islet beta cells in vivo in a subject by administering to the subject a therapeutically effective amount of heparan sulfate capable of protecting islet beta cells from reactive oxygen species or in vitro by exposing isolated islet beta cells, prior to transplantation, to a concentration of heparan sulfate that protects them from reactive oxygen species.
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申请公布号 |
CA2792610(A1) |
申请公布日期 |
2011.09.15 |
申请号 |
CA20112792610 |
申请日期 |
2011.03.11 |
申请人 |
THE AUSTRALIAN NATIONAL UNIVERSITY |
发明人 |
PARISH, CHRISTOPHER RICHARD;SIMEONOVIC, CHARMAINE;FREEMAN, CRAIG GEOFFREY |
分类号 |
A61K31/727;A61K31/737;A61P3/10;A61P37/00 |
主分类号 |
A61K31/727 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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