ENZYMATICAL MODIF ICATION OF CELL GLYCOSYLATION USING SERUM ALBUMIN AND DIVALENT CATIONS

摘要

The invention is directed to a method and composition to control and modify the status of human stem cells by changing their glycosylation, in particular sialylation and fucosylation, levels in a reaction condition where divalent cations are present and cells are kept non-adherent. The invention is further directed to the stem cell population so obtained, the glycosylation of which has been specifically altered.