Device for measuring extracellular potential and method of manufacturing the device

摘要

A device for measuring an extracellular potential of a test cell includes a substrate having a well formed in a first surface thereof and a first trap hole formed therein. The well has a bottom. The device comprises a substrate including a base, an intermediate layer on the base and made of a material different from the material of the base, and a thin plate on the intermediate layer and made of a material identical to the material of the base. A preferred substrate material is silicon on insulator (SOI). The device can retain the test cell securely and accept chemicals and the test cell to be put into the device easily.