METHOD FOR PRODUCING DIFLUOROACETIC ACID ESTER

摘要

Disclosed is a method for producing a difluoroacetic acid ester which involves at least: a reaction step in which a reaction solution is obtained by bring an alcohol represented by ROH into contact with a difluoroacetic acid fluoride (CHF2COF) in the presence of a hydrogen fluoride scavenger comprising an amide compound represented by formula (1) or a sulfone compound represented by formula (2); and a distillation step (A) in which a difluoroacetic acid ester represented by CHF2COOR is obtained as a distillate from the reaction solution obtained in the reaction step. As a consequence, said production method does not cause a drop in product yield attributable to hydrogen fluoride, which is a by-product of the mechanism of esterification reaction using difluoroacetic acid fluoride.