| 摘要 |
The present invention relates to a composition comprising an extract of Tiarella polyphylla, and tiarellic acid isolated therefrom having anti-inflammatory, anti-allergic and anti-asthmatic activity. The extract of Tiarella polyphylla and the tiarellic acid isolated therefrom shows the inhibitory effect on the LTC release in vitro test and the suppressive effect on the IgE level and the cytokine(IL-4, IL-5 and IL- 13) production, airway hyperresponsiveness, and leukocyte infiltration in OVA-induced asthmatic mice. Therefore, it can be used as the therapeutics or functional health food for treating and preventing inflammatory, allergic and asthmatic disease. |
| 申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
KIM, JUNG HEE;KIM, MI JIN;LEE, SANG KU;KWON, OK KYOUNG;KIM, EUN AH;HAN, GYOON HEE;KIM, SO YOUNG;QUAN, GUI HUA;PARK, BO YOUNG;PARK, HEA YOUNG;LEE, JOONG KU;KIM, GUN CHEOL;SHEN, GUANG HAI;KIM, DOO YOUNG;OH, SEI RYANG;AHN, KYUNG SEOP;MIN, BYUNG SUN;LEE, HYEONG KYU;KIM, JOO HEON;CHOI, SOON JA |
