ANTIVIRAL VACCINES WITH IMPROVED CELLULAR IMMUNOGENICITY
摘要
The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects.
申请公布号
EP2358757(A1)
申请公布日期
2011.08.24
申请号
EP20090828172
申请日期
2009.11.18
申请人
BETH ISRAEL DEACONESS MEDICAL CENTER;LOS ALAMOS NATIONAL SECURITY, LLC
发明人
BAROUCH, DAN, H.;KORBER, BETTE, T.;FISCHER, WILLIAM, M.