发明名称 |
Stationary phase and column using cucurbituril bonded silica gel, and separation method of taxol using the column |
摘要 |
Provided are a stationary phase and a column using a cucurbituril-bound silica gel, and a method of separating taxane using the column. The taxane separation method includes: preparing a column for taxane separation, the column being packed with a stationary phase including a cucurbituril-bound silica gel in which a cucurbituril represented by Formula 1 or 2 is covalently bound to a modified silica gel represented by Formula 3; dissolving a taxane powder in a solvent to prepare a taxane-containing solution; applying the taxane-containing solution to the column; supplying a mobile-phase solvent to the column to obtain a taxane extract from the column; and purifying taxane from the taxane extract. Therefore, highly purified taxane can be separated from a low-purity crude taxane extract.
|
申请公布号 |
US8002987(B2) |
申请公布日期 |
2011.08.23 |
申请号 |
US20060092663 |
申请日期 |
2006.03.24 |
申请人 |
POSTECH ACADEMY-INDUSTRY FOUNDATION |
发明人 |
KIM KIMOON;PARK KYENG-MIN;KO YOUNG-HO;SELVAPALAM NARAYANAN;NAGARAJAN ERUMAIPATTY R |
分类号 |
B01D15/08 |
主分类号 |
B01D15/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|