P19ARF, HMGA2 AND MDM2 FOR USE IN THE DIAGNOSIS AND TREATMENT OF ABERRANT CELL GROWTH

摘要

Provided are novel methods and compositions for the diagnosis, prognosis and treatment of leiomyomas, in particular uterine leiomyoma (UL). In addition, methods of identifying antitumor agents are described. Furthermore, novel methods and compositions are provided for the treatment of diseases characterized by an aberrant growth of mesenchymal stem cells and their descendants and for the treatment of obesity are disclosed.