发明名称 |
ORAL ANTIDEPRESSANT FORMULATION WITH REDUCED EXCIPIENT LOAD |
摘要 |
<p>Provided are methods for reducing the excipient load of pharmaceutical formulations containing 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin 10,10-dioxide as the active pharmaceutical ingredient, and compositions related thereto. In particular, provided is a pharmaceutical product comprising 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin 10, 10- dioxide and a stabilizer admixed throughout a solid-form unilamellar matrix, wherein the ratio of 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin 10,10-dioxide to stabilizer ranges from about 2:3 to about 1 :10, and related methods of forming the pharmaceutical product.</p> |
申请公布号 |
WO2011096953(A1) |
申请公布日期 |
2011.08.11 |
申请号 |
WO2010US46130 |
申请日期 |
2010.08.20 |
申请人 |
CENERX BIOPHARMA, INC.;CHEN, ANDREW;CHEN, HAILIANG;FREE, JAMES CECIL;KESHTMAND, MAJID;RAHMAN, MOHAMMED ABDUL;LOOK, SALLY |
发明人 |
CHEN, ANDREW;CHEN, HAILIANG;FREE, JAMES CECIL;KESHTMAND, MAJID;RAHMAN, MOHAMMED ABDUL;LOOK, SALLY |
分类号 |
A61K31/39;A61K9/133;A61K9/14;A61K47/30;A61P25/00;A61P25/24 |
主分类号 |
A61K31/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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