| 发明名称 |
NPC1L1 (NPC3) and methods of use thereof |
| 摘要 |
The present invention provides human, rat and mouse NPC1L1 polypeptides and polynucleotides encoding the polypeptides. Also provided are methods for detecting agonists and antagonists of NPC1L1. Inhibitors of NPC1L1 can be used for inhibiting intestinal cholesterol absorption in a subject. |
| 申请公布号 |
EP2348046(A1) |
申请公布日期 |
2011.07.27 |
| 申请号 |
EP20100013138 |
申请日期 |
2003.12.16 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
ALTMANN, SCOTT W.;MURGOLO, NICHOLAS J.;WANG, LU QUAN;GRAZIANO, MICHAEL P. |
| 分类号 |
C07K14/705;A01K67/00;A01K67/027;A01K67/033;A61K49/00;C12N15/85;G01N33/50 |
主分类号 |
C07K14/705 |
| 代理机构 |
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