摘要 |
A process for the preparation of 1-phenyl-3-dimethylaminopropane derivatives of formula (I) and its pharmaceutically acceptable salts thereof from cyano intermediate of formula (II), wherein R1 can be selected from -OR2, halo, -CH2OR2, -SR2, -SOR2, SO2R2, -SO3H, -NO2, -NR2R2', -CONR2R2', carboxylic esters, sulfonate esters or phosphate esters, R2 and R2' can be same or different, and can be selected from hydrogen, alkyl, aryl, aralkyl, heteroaryl, -COR2", -P03(R2")2 wherein R2" can be selected from alkyl, aryl, aralkyl, heteroaryl and the like. |
申请人 |
IND-SWIFT LABORATORIES LIMITED;BHIRUD, SHEKHAR, BHASKAR;JOHAR, PERMINDER, SINGH;SHARMA, EKTA;JAMSHAD, DANISH;PRAJAPATY, RAMKARAN |
发明人 |
BHIRUD, SHEKHAR, BHASKAR;JOHAR, PERMINDER, SINGH;SHARMA, EKTA;JAMSHAD, DANISH;PRAJAPATY, RAMKARAN |