METHOD FOR MANUFACTURING SUSTAINED RELEASE MICROSPHERE BY SOLVENT FLOW EVAPORATION METHOD.

摘要

The present invention relates to a method for manufacturing a sustained release microsphere which is able to continuously control the release of a drug. More specifically, the present invention relates to a method for manufacturing a sustained release microsphere through a solvent flow evaporation method using a cosolvent when manufacturing a microsphere in which a drug is sealed in a carrier comprising biodegradable polymers. Thus, early excessive release of a physiologically active substance is suppressed so the physiologically active substance can be continuously and uniformly released in the body.