发明名称 |
Detection and Treatment of Glyco-Enzyme-Related Disease |
摘要 |
The present invention relates to the prevention and treatment of a disease, preferably brain cancer, by administration of an isolated DNA molecule comprising a gene encoding a protein having glycosyltransferase activity to a cell involved in the disease which is preferably a glioblastoma cell. A method of treating brain cancer is provided in which a tumor cell is transfected either ex vivo or in vivo with a composition comprising a DNA molecule that encodes a protein having glycosyltransferase activity resulting in inhibition of the growth or function of that cell.
|
申请公布号 |
US2011150840(A1) |
申请公布日期 |
2011.06.23 |
申请号 |
US20100793539 |
申请日期 |
2010.06.03 |
申请人 |
MOSKAL JOSEPH R;YAMAMOTO HIROTAKA |
发明人 |
MOSKAL JOSEPH R.;YAMAMOTO HIROTAKA |
分类号 |
A61K35/76;A61K31/7088;A61K48/00;A61P35/00;C07H21/04;C12N7/01;C12N9/10 |
主分类号 |
A61K35/76 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|