发明名称 SUBSTITUTED PYRAZINONE MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS AND METHODS
摘要 The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I wherein R1, R2, R3, R8, and R9 are defined herein. Additionally, the present application provides pharmaceutical compositions containing at least one compound according to Formula I and optionally at least one additional therapeutic agent. Finally, the present application provides methods for treating a patient suffering from an MCHR-1 modulated disease or disorder such as, for example, obesity, diabetes, depression or anxiety by administration of a therapeutically effective dose of a compound according to Formula I.
申请公布号 US2011144060(A1) 申请公布日期 2011.06.16
申请号 US201113028570 申请日期 2011.02.16
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 STEIN PHILIP D.;BISAHA SHARON N.;AHMAD SALEEM;NGU KHEHYONG;WASHBURN WILLIAM N.
分类号 A61K31/4965;A61K31/497;A61K31/675;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P17/00;A61P25/00;A61P25/16;A61P25/22;A61P25/24;A61P25/30;C07D241/18;C07D401/04;C07D401/10;C07D401/12;C07D403/10;C07D405/10;C07D413/12;C07D417/12;C07F9/6509 主分类号 A61K31/4965
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