发明名称 BIFUNCTIONAL CHELATING AGENT FOR ACTINIUM
摘要 The invention concerns a ligand comprising (I) wherein n is an integer from 1 to 5 Y is CO2H or PO3H2T represents -X or -phenyl-X, wherein X represents NO2, NH2, NCS, NHCOCH2-Z, NHCO-W-COCNHS, -NH-Q, -NHCS-Q, -NHCOCH2-Q, or NHCO(CH2)m-Q where Q is a hapten chosen from the group consisting of steroids, enzymes, proteins, monoclonal antibodies, chimeric antibodies, or fragments thereof or any activated linker ready for coupling reaction, W is -(CH2)m- m is an integer from 1 to 10 Z is chloride, bromide or iodine.
申请公布号 CA2458267(C) 申请公布日期 2011.06.14
申请号 CA20022458267 申请日期 2002.09.13
申请人 EUROPEAN COMMUNITY 发明人 OUADI, ALI;GESTIN, JEAN-FRANCOIS;APOSTOLIDIS, CHRISTOS
分类号 C07D259/00;G01T1/161;A61K31/395;A61K31/56;A61K38/00;A61K38/43;A61K39/395;A61K49/00;A61K51/00;A61K51/04;A61K51/10;A61P35/00;A61P35/02;A61P39/02;B01J20/22;B01J20/281;C07B59/00;C07F5/00;C07F9/6524;C07J43/00 主分类号 C07D259/00
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