发明名称 |
NEW THERAPEUTIC AGENT FOR MALIGNANT MESOTHELIOMA AND IMMUNOSTIMULANT |
摘要 |
<p>According to the present invention, a method for treating malignant mesothelioma using REIC/Dkk-3 and a therapeutic agent for malignant mesothelioma comprising REIC/Dkk-3 are provided. A mesothelioma therapeutic agent is provided, comprising the following REIC/Dkk-3 DNA or a vector comprising the DNA as an active ingredient:
(a) a DNA consisting of the nucleotide sequence shown in SEQ ID NO: 1; or
(b) a DNA hybridizing under stringent conditions to a DNA consisting of a nucleotide sequence complementary to the nucleotide sequence shown in SEQ ID NO: 1 and encoding a protein having apoptosis-inducing activity and IL-7 production-accelerating activity in cells.</p> |
申请公布号 |
EP2327779(A1) |
申请公布日期 |
2011.06.01 |
申请号 |
EP20090803076 |
申请日期 |
2009.07.30 |
申请人 |
NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY;MOMOTARO-GENE INC. |
发明人 |
KUMON, HIROMI;NASU, YASUTOMO;KASHIWAKURA, YUJI;WATANABE, MASAMI;HUH, NAM-HO;SAKAGUCHI, MASAKIYO |
分类号 |
C12N15/09;A61K35/00;A61K35/76;A61K48/00;A61P11/00;A61P37/04 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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