发明名称 |
METHOD FOR PREPARING GINTONIN, WHICH IS A NOVEL GLYCOLIPOPROTEIN FROM PANAX GINSENG, AND GINTONIN, WHICH IS A NOVEL GLYCOLIPOPROTEIN, PREPARED BY THE METHOD |
摘要 |
The present invention relates to a method for preparing gintonin, which is a novel glycolipoprotein isolated and identified from Panax ginseng, to gintonin, which is a novel glycolipoprotein isolated and identified from Panax ginseng, prepared by the method, and to the use of gintonin, which is a novel glycolipoprotein. The gintonin, which is a novel glycolipoprotein, according to the present invention temporarily causes an increase in free Ca2+ in cytoplasm, and activates a calcium-activated chloride channel (CaCC) which is intrinsically present in Xenopus oocytes, thus increasing an intracellular calcium concentration. Therefore, gintonin, which is a novel glycolipoprotein, according to the present invention not only can be effectively used in preventing and treatingdiseases caused by a reduction in calcium concentration, but also exhibits superior effects in a variety of intracellular calcium-activated physiological activities or the like, such as adaptogenic activities, immunity-increasing activities, sexual-function-strengthening activities, nervous system protection and activation, vascularization, and anti-diabetic activities. |
申请公布号 |
WO2011062354(A2) |
申请公布日期 |
2011.05.26 |
申请号 |
WO2010KR05304 |
申请日期 |
2010.08.12 |
申请人 |
KONKUK UNIVERSITY COOPERATION CORP.;NAH, SEUNG YEOL;PYO, MI KYUNG;CHOI, SUN HYE;LEE, BYUNG HWAN;SHIN, TAE JOON |
发明人 |
NAH, SEUNG YEOL;PYO, MI KYUNG;CHOI, SUN HYE;LEE, BYUNG HWAN;SHIN, TAE JOON |
分类号 |
C07K14/415;A61K36/258;C07K1/16 |
主分类号 |
C07K14/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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