发明名称 |
Agonistic binding molecules to the human OX40 receptor |
摘要 |
The present invention provides binding molecules, such as human binding molecules, that bind to and stimulate the human OX40-receptor. The invention also provides nucleic acids encoding such binding molecules. Methods for producing such binding molecules are also provided by the present invention. The binding molecules and nucleic acids are useful in the stimulation of human T-cells and can be used to enhance antigen-specific immune responses.
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申请公布号 |
US2011123552(A1) |
申请公布日期 |
2011.05.26 |
申请号 |
US20090383330 |
申请日期 |
2009.03.23 |
申请人 |
CRUCELL HOLLAND B.V. |
发明人 |
BAKKER ALEXANDER BERTHOLD HENDRIK;MEESTER-ROOD PAULINE MARIE LOUISE;BAKKER ADRIANUS QUIRINUS |
分类号 |
A61K39/395;A61K31/00;A61K49/00;A61K51/10;A61P31/00;A61P35/00;A61P37/02;A61P37/04;C07H21/00;C07K16/28;C12N5/10;C12N15/63;C12P21/02;G01N33/564;G01N33/68 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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