| 发明名称 |
SUBSTITUTED ISOQUINOLINES AND THEIR USE AS RHO-KINASE INHIBITORS |
| 摘要 |
The invention relates to 6-substituted isoquinoline and isoquinoline derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds. |
| 申请公布号 |
PT2132194(E) |
申请公布日期 |
2011.05.16 |
| 申请号 |
PT20070856891T |
申请日期 |
2007.12.19 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
OLIVER PLETTENBURG;MATTHIAS L?HN;KATRIN LORENZ;JOCHEN GOERLITZER |
| 分类号 |
C07D401/12;A61K31/4725;A61P3/00;A61P7/00;A61P9/00;A61P25/00;C07D401/14;C07D405/14;C07D451/06 |
主分类号 |
C07D401/12 |
| 代理机构 |
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代理人 |
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