发明名称 NOVEL SACCHARIDE PRIMER AND USE THEREOF
摘要 The present invention can provide a novel saccharide primer, which makes it possible to efficiently synthesize a sugar chain, and a method for using the primer. According to the present invention, the saccharide primer of the present invention is a saccharide primer having an alkenyl chain that has one or more double bonds in a position other than the alkyl chain terminal, and represented by the following general formula (I): Lac-O-Ck:m(n)   General formula (I) In the general formula (I), Ck represents an alkenyl chain, m represents a total number of double bonds, and n represents a position of the double bond in the alkenyl chain. Here, k is preferably an integer in the range of 8 to 14, and particularly 12 or 13. In addition, when m is 1, n is an integer satisfying 1≦̸n≦̸k−2; and when m satisfies 2≦̸m≦̸k−1, n is a plurality of integers satisfying 1≦̸n≦̸k−1. An example of the primer is the following general formula (II): A sugar chain synthesized by using the saccharide primer of the present invention can be used for producing a sugar chain array, for synthesizing a glycopeptide, and the like.
申请公布号 US2011111986(A1) 申请公布日期 2011.05.12
申请号 US20080808811 申请日期 2008.12.18
申请人 KEIO UNIVERSITY 发明人 SATO TOSHINORI;NAKAJIMA HIDEKI
分类号 C40B40/12;C07H1/00;C07H15/10;C07K1/107;C07K2/00;C12P19/44;C40B50/14 主分类号 C40B40/12
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