发明名称 |
1,2-dihydropyridine compounds, manufacturing method thereof and use thereof |
摘要 |
The present invention provides a novel compound having an excellent AMPA receptor inhibitory action and/or kainate inhibitory action. A compound represented by the following formula, a salt thereof or hydrates thereof. In the formula, Q indicates NH, O or S; and R1, R2, R3, R4 and R5 are the same as or different from each other and each indicates hydrogen atom, a halogen atom, a C1-6 alkyl group or a group represented by the formula—X-A (wherein X indicates a single bond, an optionally substituted C1-6 alkylene group etc.; and A indicates an optionally substituted C6-14 aromatic hydrocarbocyclic group or 5- to 14-membered aromatic heterocyclic group etc.).
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申请公布号 |
US7939549(B2) |
申请公布日期 |
2011.05.10 |
申请号 |
US20090395378 |
申请日期 |
2009.02.27 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD. |
发明人 |
NAGATO SATOSHI;UENO KOHSHI;KAWANO KOKI;NORIMINE YOSHIHIKO;ITO KOICHI |
分类号 |
C07D401/04;A61K;A61K31/44;A61P;A61P1/08;A61P9/10;A61P13/02;A61P21/04;A61P25/00;A61P25/02;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/28;A61P25/30;A61P43/00;C07D;C07D213/64;C07D213/65;C07D213/69;C07D213/70;C07D213/73;C07D213/74;C07D213/75;C07D213/76;C07D213/81;C07D213/84;C07D213/89;C07D401/14;C07D405/04;C07D405/14;C07D409/04;C07D409/14;C07D413/04;C07D413/14;C07D417/04;C07D417/14;C07D471/04;C07D471/06;C07F7/18 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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