发明名称 NOVEL METHOD FOR THE PRODUCTION OF SULPHONYLPYRROLES AS HDAC INHIBITORS
摘要 Process for the preparation of a compound of formula (I) wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, comprising the step of reacting an acrylic acid chloride compound of formula (II′): wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, with aqueous hydroxylamine and optionally converting the resulting compound into an acid addition salt thereof.
申请公布号 US2011105568(A1) 申请公布日期 2011.05.05
申请号 US20090921928 申请日期 2009.03.11
申请人 4SC AG 发明人 MULLER MATTHIAS;MULLER BERND;MAIER THOMAS
分类号 A61K31/40;A61K31/4155;A61K31/4439;A61P35/00;C07D207/48;C07D403/10;C07D409/14 主分类号 A61K31/40
代理机构 代理人
主权项
地址