发明名称 PYRIMIDINE SULFONAMIDE DERIVATIVE AS CHEMOKINE RECEPTOR MODULATOR
摘要 PROBLEM TO BE SOLVED: To provide certain heterocyclic compounds, a method and intermediate for use in production of the compounds, pharmaceutical compositions including the compounds and use thereof in treatment. SOLUTION: There are provided the compound of formula (1) (wherein R<SP>1</SP>-R<SP>3</SP>and X are defined separately), or a pharmaceutically acceptable salt, solvate or in vivo hydrolyzable ester thereof and the pharmaceutical compositions comprising these, all for use in the treatment of chemokine mediated diseases and disorders. COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011084576(A) 申请公布日期 2011.04.28
申请号 JP20110013745 申请日期 2011.01.26
申请人 ASTRAZENECA AB 发明人 CHESHIRE DAVID RANULF;COX RHONA JANE;MEGHANI PREMJI;PRESTON CHERYLIN FRANCIS;SMITH MICHAEL NEAL;STONEHOUSE JEFFREY PAUL
分类号 C07D239/42;A61K31/506;A61K31/5377;A61K31/551;A61P1/04;A61P11/00;A61P11/06;A61P17/06;A61P19/02;A61P19/10;A61P29/00;A61P35/00;A61P37/08;A61P43/00;C07D239/47;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D413/12;C07D417/12;C07D487/14 主分类号 C07D239/42
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