ON-DEMAND AND REVERSIBLE DRUG RELEASE BY EXTERNAL CUE
摘要
The invention provides a method to release drugs from a polymer matrix upon demand without degrading the matrix. By applying ultrasound to a self-healable polymer matrix in physiological environment, compounds of both low-molecular and high-molecular weights encapsulated in the matrix are delivered at controlled rates, while the integrity and stiffness of the matrix are unaffected.
申请公布号
WO2010093528(A3)
申请公布日期
2011.03.31
申请号
WO2010US22769
申请日期
2010.02.01
申请人
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;ZHAO, XUANHE;HUEBSCH, NATHANIEL, D.;MOONEY, DAVID, J.;SUO, ZHIGANG