发明名称 DRUG ACTIVATION SYSTEM
摘要 The present invention discloses a drug activator carrier comprising: a) particles having a metallic or metallic oxide core prepared from a paramagnetic material, said metallic core being coated with a coating material selected from polymer, metal or metal oxide; b) a biological material, having reductase activity, bound onto the metal coating the particles of step a), and wherein said biological material is capable of activating non-toxic pro-drugs into active and toxic drugs suitable for treating a disease; said drug activator carrier allowing targeted delivery of the toxic drug.
申请公布号 WO2011026898(A2) 申请公布日期 2011.03.10
申请号 WO2010EP62871 申请日期 2010.09.02
申请人 BANGOR UNIVERSITY;GWENIN, CHRISTOPHER;KALAJI, MAHER;ROBERTS, VANESSA 发明人 GWENIN, CHRISTOPHER;KALAJI, MAHER;ROBERTS, VANESSA
分类号 A61K47/48;A61P35/00 主分类号 A61K47/48
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